KMID : 0360220130540091365
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Journal of the Korean Ophthalmological Society 2013 Volume.54 No. 9 p.1365 ~ p.1370
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Reproducibility of Choroidal Thickness in Normal Korean Eyes Using Two Spectral Domain Optical Coherence Tomography
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Lee Kwang-Hyun
Lee Sung-Chul Lee Seung-Kyu
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Abstract
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Purpose: To investigate the reproducibility of choroidal thickness measurements in healthy Koreans using two spectral domain optical coherence tomography (SD-OCT) instruments: Zeiss Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA) and Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany).
Methods: Images were obtained in 60 eyes of 30 healthy undilated volunteers without ocular pathology in a clinical setting. The choroid was imaged in all subjects using Cirrus HD 1-line raster and Spectralis enhanced depth imaging (EDI). The choroid was measured subfoveally, 1500 ¥ìm temporal, and 1500 ¥ìm nasal to the fovea. All measurements were performed by two independent observers. One-way analysis of variance (ANOVA), Pearson correlation, and Bland?Altman analysis were used to compare measurements.
Results: The study group consisted of 15 males and 15 females. The mean age was 50.73 ¡¾ 15.09 years (range, 24-75 years). There was no significant difference in the mean choroidal thickness (p > 0.05) between systems for any location. The choroidal thickness measurements using two instruments (Cirrus vs. Spectralis) were also strongly correlated (p < 0.001).
Conclusions: In the present study of healthy Korean adults, good reproducibility was observed between choroidal thickness measurements of images obtained from Cirrus and Spectralis.
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KEYWORD
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Choroidal thickness, Optical coherence tomography, Reproducibility of results
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